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CS-W001157 4
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1-Amino-5-hexene

  • CAS No. 34825-70-2

  • Cat. No. CS-0210385
  • Purity≥95%
  • MDL No.MFCD02258452

*For research and further manufacturing use only, not for direct human use.

1-Amino-5-hexene|CS-0210385

Structure of 34825-70-2

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General Information

  • CAS No. 34825-70-2
  • Cat. No. CS-0210385
  • Purity ≥95%
  • MDL No. MFCD02258452
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃N
  • Molecular Weight 99.17
  • Synonym(s) Hex-5-en-1-amine
  • SMILES C=CCCCCN

Description

1-Amino-5-hexene features a primary amine group conjugated to a terminal alkene, enabling direct functionalization in cross-coupling and cycloaddition reactions. This bifunctional scaffold supports modular synthesis of complex organic architectures under mild conditions.

Application

1-Amino-5-hexene serves as a versatile bifunctional building block for synthesizing nitrogen-containing heterocycles and functionalized alkenes. Its terminal amine and alkene functionalities enable selective transformations in amide coupling, Michael additions, and catalytic hydrogenation. The molecule exhibits good bench stability and compatibility with common protecting groups, facilitating straightforward purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1
    • Hex-5-enenitrile|CS-0327133
      5048-19-1
    • ~75%
    • In-stock
      1-Amino-5-hexene|CS-0210385
      34825-70-2

    References

    • Samii, Zakaria K. M. Abd El; Ashmawy, Mohamed I. Al; Mellor, John M. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2517 - 2522
  • Route2

    References

    • MASSACHUSETTS INSTITUTE OF TECHNOLOGY; TRUSTEES OF BOSTON COLLEGE; HOVEYDA, Amir H.; YU, Miao; WANG, Chenbo; SCHROCK, Richard R. Patent: WO2012/167171 A2, 2012 ; Location in patent: Page/Page column 179-180 ;
  • Route3
    • null|null
      52898-33-6
    • ~95%
    • In-stock
      1-Amino-5-hexene|CS-0210385
      34825-70-2

    References

    • Smith, Brian J.; Sulikowski, Gary A. Angewandte Chemie - International Edition, 2010 , vol. 49, # 9 p. 1599 - 1602

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2734
Class : 8,3
Packing Group : Ⅱ
Hazard Statements : H225-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.3014
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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