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CS-W001157 4
Total: USD 88.00

[1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde

  • CAS No. 614750-81-1

  • Cat. No. CS-W018214
  • Purity≥95%
  • MDL No.MFCD11112116

*For research and further manufacturing use only, not for direct human use.

[1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde|CS-W018214

Structure of 614750-81-1

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General Information

  • CAS No. 614750-81-1
  • Cat. No. CS-W018214
  • Purity ≥95%
  • MDL No. MFCD11112116
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O
  • Molecular Weight 147.14
  • Synonym(s) [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde
  • SMILES O=CC1=CN2C(C=C1)=NC=N2

Description

This [1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde features a rigid heteroaromatic core fused with a reactive aldehyde group, enabling direct integration into click chemistry and bioconjugation workflows. The electron-deficient triazolopyridine scaffold enhances binding affinity in target-directed synthesis, while the aldehyde facilitates site-specific derivatization under mild conditions.

Application

[1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient construction of fused triazole-pyridine scaffolds. The aldehyde functionality facilitates nucleophilic addition, reductive amination, and condensation reactions with amines or hydrazines, offering reliable access to bioactive analogs. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative medicinal chemistry campaigns and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   47.26
  • LogP   0.5418
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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