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CS-W001157 4
Total: USD 88.00

Ethyl 2-furancarboxylate

  • CAS No. 614-99-3

  • Cat. No. CS-0015334
  • Purity≥97%
  • MDL No.MFCD00003237

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-furancarboxylate|CS-0015334

Structure of 614-99-3

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General Information

  • CAS No. 614-99-3
  • Cat. No. CS-0015334
  • Purity ≥97%
  • MDL No. MFCD00003237
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₃
  • Molecular Weight 140.14
  • Synonym(s) Ethyl 2-furoate
  • SMILES O=C(C1=CC=CO1)OCC

Description

Ethyl 2-furancarboxylate serves as a versatile heterocyclic building block in synthetic organic chemistry. This bench-stable ester integrates readily into cross-coupling and condensation reactions, offering high reactivity at the furan ring’s C2 position. The ethyl ester group enables straightforward functionalization, while the electron-rich furan moiety supports diverse transformations under mild conditions.

Application

Ethyl 2-furancarboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to furan-based scaffolds via coupling and functionalization reactions. Its ester group facilitates nucleophilic addition and metal-catalyzed transformations, while the furan ring provides inherent stability and compatibility with diverse reaction conditions. Widely employed in medicinal chemistry and materials science, it functions as a reliable precursor for bioactive molecules and conjugated systems.

Synthesis

  • Route1

    References

    • WAKO PURE CHEMICAL INDUSTRIES, LTD. Patent: US2010/324314 A1, 2010 ; Location in patent: Page/Page column 16 ;
  • Route2
    • null|null
      98-01-1
    • null|null
      64-17-5
    • ~93%
    • In-stock
      Ethyl 2-furancarboxylate|CS-0015334
      614-99-3

    References

    • Gopinath, Rangam; Barkakaty, Balaka; Talukdar, Bandana; Patel, Bhisma K. Journal of Organic Chemistry, 2003 , vol. 68, # 7 p. 2944 - 2947
  • Route3
    • In-stock
      Methyl 2-furoate|CS-W020101
      611-13-2
    • null|null
      105-36-2
    • ~92%
    • In-stock
      Ethyl 2-furancarboxylate|CS-0015334
      614-99-3

    References

    • Coskun, Necdet; Er, Mustafa Tetrahedron, 2003 , vol. 59, # 19 p. 3481 - 3485

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.44
  • LogP   1.4563
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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