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CS-W001157 4
Total: USD 88.00

(2R)-2-PYRROLIDINEACETIC ACID

  • CAS No. 61350-65-0

  • Cat. No. CS-0035825
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2R)-2-PYRROLIDINEACETIC ACID|CS-0035825

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General Information

  • CAS No. 61350-65-0
  • Cat. No. CS-0035825
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁NO₂
  • Molecular Weight 129.16
  • Synonym(s) (2R)-2-Pyrrolidineacetic acid
  • SMILES C1C[C@H](CC(=O)O)NC1

Description

(R)-2-(Pyrrolidin-2-yl)acetic acid features a chiral pyrrolidine ring tethered to a carboxylic acid moiety, delivering a rigid, electron-rich scaffold ideal for asymmetric synthesis. This bench-stable derivative integrates readily into peptidomimetics and bioactive molecule frameworks, offering enhanced solubility and conformational control in medicinal chemistry applications.

Application

(R)-2-(Pyrrolidin-2-yl)acetic acid serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard amide coupling and functional group manipulation. Its pyrrolidine moiety provides favorable solubility and metabolic stability, while the α–amino acid framework supports direct incorporation into peptide-like scaffolds. Bench-stable and readily purified by recrystallization, it functions reliably in both small-molecule and macrocyclic synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   0.2131
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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