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CS-W001157 4
Total: USD 88.00

N-Ethyl-N-methylaniline

  • CAS No. 613-97-8

  • Cat. No. CS-0152044
  • Purity≥97%
  • MDL No.MFCD00009038

*For research and further manufacturing use only, not for direct human use.

N-Ethyl-N-methylaniline|CS-0152044

Structure of 613-97-8

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General Information

  • CAS No. 613-97-8
  • Cat. No. CS-0152044
  • Purity ≥97%
  • MDL No. MFCD00009038
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N
  • Molecular Weight 135.21
  • Synonym(s) n-ethyl-n-methyl-benzenamin
  • SMILES CCN(C)C1=CC=CC=C1

Description

N-Ethyl-N-methylaniline is a bench-stable, electron-rich tertiary amine featuring a para-substituted aromatic ring. This compound integrates readily into synthetic transformations requiring nucleophilic nitrogen centers, offering enhanced solubility in organic media and tolerance to ambient moisture during handling.

Application

N-Ethyl-N-methylaniline serves as a versatile tertiary amine in synthetic organic chemistry, enabling efficient nucleophilic catalysis and acting as a stable, bench-ready alternative to more sensitive amines. Its moderate basicity and favorable solubility profile facilitate use in coupling reactions, phase-transfer catalysis, and as a building block for heterocyclic scaffolds. The molecule exhibits robust stability under standard reaction conditions and is readily purified by distillation or chromatography.

Synthesis

  • Route1
    • null|null
      917-64-6
    • null|null
      13657-45-9
    • ~70%
    • In-stock
      N-Ethyl-N-methylaniline|CS-0152044
      613-97-8

    References

    • Shono, Tatsuya; Matsumura, Yoshihiro; Inoue, Kenji; Ohmizu, Hiroshi; Kashimura, Shigenori Journal of the American Chemical Society, 1982 , vol. 104, # 21 p. 5753 - 5757
  • Route2
    • null|null
      124-38-9
    • null|null
      103-84-4
    • ~66%
    • In-stock
      N-Ethyl-N-methylaniline|CS-0152044
      613-97-8

    References

    • Beydoun, Kassem; Vom Stein, Thorsten; Klankermayer, Juergen; Leitner, Walter Angewandte Chemie - International Edition, 2013 , vol. 52, # 36 p. 9554 - 9557 Angew. Chem., 2013 , vol. 125, # 36 p. 9733 - 9736
  • Route3
    • null|null
      31469-15-5
    • In-stock
      N-Methylacetanilide|CS-0155055
      579-10-2
    • ~10%
    • In-stock
      N-Ethyl-N-methylaniline|CS-0152044
      613-97-8
    • null|null
      1445316-10-8

    References

    • Organic Letters, , vol. 15, # 13 p. 3452 - 3455

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H311-H331-H402-H412
Precautionary Statements : P210-P261-P264-P270-P271-P273-P280-P362-P370+P378-P403+P233-P403+P235-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   2.1427
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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