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CS-W001157 4
Total: USD 88.00

N'-Hydroxybenzimidamide

  • CAS No. 613-92-3

  • Cat. No. CS-W017758
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N'-Hydroxybenzimidamide|CS-W017758

Structure of 613-92-3

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General Information

  • CAS No. 613-92-3
  • Cat. No. CS-W017758
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O
  • Molecular Weight 136.15
  • Synonym(s) N'-Hydroxybenzenecarboximidamide
  • SMILES N/C(C1=CC=CC=C1)=N\O

Description

N'-Hydroxybenzimidamide features a hydroxylated imidamide core that enables direct participation in nitration and amidation cascades. This bench-stable reagent delivers efficient functional group interconversion under mild conditions, pairing well with electrophilic partners in synthetic sequences.

Application

N'-Hydroxybenzimidamide serves as a reliable precursor for amidine and imidazole-based heterocycles, enabling efficient access to bioactive scaffolds through standard condensation and cyclization protocols. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward incorporation into medicinal chemistry workflows, particularly in the synthesis of kinase inhibitors and antiviral agents.

Synthesis

  • Route1
    • null|null
      100-47-0
    • ~99%
    • In-stock
      N'-Hydroxybenzimidamide|CS-W017758
      613-92-3

    References

    • Lee, Wai Mun Patent: US2009/112024 A1, 2009 ; Location in patent: Page/Page column 27 ;
  • Route2
    • null|null
      90557-80-5
    • ~%
    • In-stock
      N'-Hydroxybenzimidamide|CS-W017758
      613-92-3
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4

    References

    • US2012/77876 A1, ; Page/Page column 7; 9 ;
  • Route3
    • null|null
      942-87-0
    • ~0%
    • In-stock
      5-Methyl-3-phenyl-1,2,4-oxadiazole|CS-0126655
      1198-98-7
    • In-stock
      N'-Hydroxybenzimidamide|CS-W017758
      613-92-3

    References

    • Otaka, Hiromichi; Ikeda, Junya; Tanaka, Daisuke; Tobe, Masanori Tetrahedron Letters, 2014 , vol. 55, # 5 p. 979 - 981

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.61
  • LogP   0.7811
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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