(S)-3-Aminopropane-1,2-diol

Name: (S)-3-Aminopropane-1,2-diol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 61278-21-5
Cat. No. CS-W017771
Purity≥97%
MDL No.MFCD00798260

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 61278-21-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 61278-21-5
Cat. No. CS-W017771
Purity ≥97%
MDL No. MFCD00798260
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₉NO₂
Molecular Weight 91.11
Synonym(s) Amino-1,2-propanediol, (S)-3-
SMILES OC[C@@H](O)CN

Description

(S)-3-aminopropane-1,2-diol features a chiral center with defined stereochemistry, enabling precise incorporation into bioactive molecules. This hydroxylated amine scaffold delivers enhanced solubility and hydrogen-bonding capacity, supporting efficient integration in peptide mimetics and kinase inhibitor design under standard bench conditions.

Application

(S)-3-Aminopropane-1,2-diol serves as a key chiral building block for the synthesis of bioactive heterocycles and amino acid derivatives. Its three contiguous functional groups—primary amine, primary alcohol, and secondary alcohol—enable diverse transformations under standard conditions. The molecule exhibits excellent bench stability and facilitates efficient derivatization with minimal protection requirements, making it well-suited for modular synthetic sequences in medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  616-30-8
- ~%
- In-stock
  
  61278-21-5
- In-stock
  
  66211-46-9
References
- WO2010/148191 A2, ; Page/Page column 45-49; 59 ;
Route2
- In-stock
  
  82954-65-2
- ~90%
- In-stock
  
  61278-21-5
References
- Danklmaier, Johann; Hoenig, Helmut Liebigs Annalen der Chemie, 1988 , p. 1149 - 1154
Route3
- 57044-25-4
- ~%
- In-stock
  
  61278-21-5
References
- Journal of Medicinal Chemistry, , vol. 37, # 22 p. 3707 - 3716

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3259
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 66.48
LogP -1.7017
H_Acceptors 3
H_Donors 3
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

(S)-3-Aminopropane-1,2-diol sigma(S)-3-Aminopropane-1,2-diol manufacturer(S)-3-Aminopropane-1,2-diol price(S)-3-Aminopropane-1,2-diol structure(S)-3-Aminopropane-1,2-diol SDSbuy (S)-3-Aminopropane-1,2-diol(S)-3-Aminopropane-1,2-diol supplier(S)-3-Aminopropane-1,2-diol uses(S)-3-Aminopropane-1,2-diol molecular weightprice of (S)-3-Aminopropane-1,2-diol(S)-3-Aminopropane-1,2-diol chemical name formula of (S)-3-Aminopropane-1,2-diol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(S)-3-Aminopropane-1,2-diol

CAS No. 61278-21-5

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words