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CS-W001157 4
Total: USD 88.00

5-Ethynyl-2'-deoxyuridine

  • CAS No. 61135-33-9

  • Cat. No. CS-0065850
  • Purity≥97%
  • MDL No.MFCD01675687

*For research and further manufacturing use only, not for direct human use.

5-Ethynyl-2'-deoxyuridine|CS-0065850

Structure of 61135-33-9

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General Information

  • CAS No. 61135-33-9
  • Cat. No. CS-0065850
  • Purity ≥97%
  • MDL No. MFCD01675687
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂N₂O₅
  • Molecular Weight 252.23
  • Synonym(s) EdU
  • SMILES O[C@H]1C[C@H](N2C(NC(C(C#C)=C2)=O)=O)O[C@@H]1CO

Description

5-Ethynyl-2-deoxyuridine (EdU) is a thymidine analogue that can be incorporated into cellular DNA for cell proliferation studies. The incorporated nucleoside analogue can be detected by a copper-catalyzed click reaction with a fluorescent azide.5-Ethynyl-2-deoxyuridine (EdU) is used for: Labeling newly synthesized DNA during replication Cell proliferating assay studies Cell cycle analysisFor information on Baseclick kits containing all the reagents for the assays see: Baseclick kitsFor a listing of the Baseclick kits see: Baseclick kits

Synthesis

  • Route1
    • null|null
      151362-01-5
    • ~91%
    • In-stock
      5-Ethynyl-2'-deoxyuridine|CS-0065850
      61135-33-9

    References

    • Journal of Organic Chemistry, , vol. 58, # 24 p. 6614 - 6619
  • Route2

    References

    • Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 50, # 7 p. 649 - 655
  • Route3
    • null|null
      77875-91-3
    • ~%
    • In-stock
      5-Ethynyl-2'-deoxyuridine|CS-0065850
      61135-33-9

    References

    • Tetrahedron Letters, , vol. 22, p. 421 - 424

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H340-H361
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   104.55
  • LogP   -1.8414
  • H_Acceptors   6
  • H_Donors   3
  • Rotatable_Bonds   2

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