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Hexahydro-1H-furo[3,4-c]pyrrole hydrochloride

  • CAS No. 60889-33-0

  • Cat. No. CS-0071682
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Hexahydro-1H-furo[3,4-c]pyrrole hydrochloride|CS-0071682

Structure of 60889-33-0

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General Information

  • CAS No. 60889-33-0
  • Cat. No. CS-0071682
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO
  • Molecular Weight 149.62
  • Synonym(s) hexahydro-1H-furo[3,4-c]pyrrole hydrogen chloride
  • SMILES C12COCC1CNC2.Cl

Description

Hexahydro-1H-furo[3,4-c]pyrrole hydrochloride is a bench-stable, moisture-tolerant heterocyclic scaffold featuring a saturated pyrrolidine core fused to a tetrahydrofuran ring. This nitrogen-rich structure serves as a key building block in medicinal chemistry, offering enhanced solubility and metabolic stability for targeted drug discovery applications.

Application

Hexahydro-1H-furo[3,4-c]pyrrole hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-containing scaffolds. Its saturated furanopyrrole core exhibits good bench stability and functional group tolerance, facilitating downstream derivatization via standard amine alkylation or acylation protocols. The hydrochloride salt form enhances solubility and crystallinity, simplifying purification and handling in synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.274
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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