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Structure of 60629-92-7
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This cyclopropane-based diacid features a rigid, sterically constrained biaryl scaffold that enhances structural stability and directs regioselective functionalization. The carboxylic acid groups enable efficient conjugation and solubility tuning in polar media, supporting applications in ligand design and molecular scaffold development.
[1,1'-Bi(cyclopropane)]-1-carboxylic acid serves as a robust scaffold for constructing sterically constrained biaryl systems in medicinal chemistry. Its cyclopropyl moieties confer enhanced metabolic stability and rigidity, facilitating precise spatial orientation in target-binding interactions. The carboxylic acid group enables direct derivatization or salt formation, improving solubility and purification. This compound exhibits excellent bench stability and functional group tolerance, making it ideal for iterative synthesis campaigns and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: