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Structure of 60-25-3
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Blocking nicotinic acetylcholine receptor signaling at the neuromuscular junction, Hexamethonium chloride (CAS 60-25-3) inhibits ion flux through ligand-gated channels by stabilizing the closed conformation of α-subunit interfaces.
Hexamethonium chloride (CAS 60-25-3) blocks nicotinic receptor responses to agonists by acting as a potent competitive antagonist at neuronal junctions. This enables precise control over autonomic signaling. Researchers leverage this property to dissect mechanosensitivity in viscerofugal neurons, revealing key pathways in visceral sensory processing.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364
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Lot numbers can be found on the outside label of a product: