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CS-W001157 4
Total: USD 88.00

Decamethonium (Bromide)(Reagent for Ion-Pair Chromatography,99%)

  • CAS No. 541-22-0

  • Cat. No. CS-0148660
  • Purity≥99.0%,for Ion-Pair Chromatography
  • MDL No.MFCD00011779

*For research and further manufacturing use only, not for direct human use.

Decamethonium (Bromide)(Reagent for Ion-Pair Chromatography,99%)|CS-0148660

Structure of 541-22-0

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General Information

  • CAS No. 541-22-0
  • Cat. No. CS-0148660
  • Purity ≥99.0%,for Ion-Pair Chromatography
  • MDL No. MFCD00011779
  • Storage 4°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₈Br₂N₂
  • Molecular Weight 418.29
  • Synonym(s) None
  • SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]

Description

Blocking nicotinic acetylcholine receptors at the neuromuscular junction, Decamethonium bromide (CAS 541-22-0) induces depolarization-induced paralysis through sustained channel activation and subsequent desensitization in skeletal muscle preparations.

Application

Decamethonium bromide (CAS 541-22-0) induces rapid, sustained paralysis in duck embryo models by irreversibly blocking neuromuscular junctions. It disrupts acetylcholine receptor signaling. Researchers use this effect to study embryonic motor development under controlled immobilization conditions.

Synthesis

  • Route1
    • In-stock
      1,10-Dibromodecan|CS-W009956
      4101-68-2
    • null|null
      75-50-3
    • ~53%
    • In-stock
      Decamethonium (Bromide)(Reagent for Ion-Pair Chromatography,99%)|CS-0148660
      541-22-0

    References

    • Tischer, Maximilian; Sologub, Ludmilla; Pradel, Gabriele; Holzgrabe, Ulrike Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 9 p. 2998 - 3003
  • Route2

    References

    • Baer, Andrew J.; Macartney, Donal H. Organic and Biomolecular Chemistry, 2005 , vol. 3, # 8 p. 1448 - 1453

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   -2.4724
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   11

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