(R)-tert-Butyl 2-aminopropanoate

Name: (R)-tert-Butyl 2-aminopropanoate
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CAS No. 59624-87-2
Cat. No. CS-0437324
Purity≥98%
MDL No.MFCD10001351

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(R)-tert-Butyl 2-aminopropanoate|CS-0437324

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General Information

CAS No. 59624-87-2
Cat. No. CS-0437324
Purity ≥98%
MDL No. MFCD10001351
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₅NO₂
Molecular Weight 145.20
Synonym(s) tert-butyl (2R)-2-aminopropanoate
SMILES N[C@H](C)C(OC(C)(C)C)=O

Description

(R)-tert-Butyl 2-aminopropanoate is a chiral building block featuring a stereodefined amino group and a bulky tert-butyl ester. This configuration enables selective incorporation into peptide backbones and asymmetric synthesis, where the steric bulk enhances diastereoselectivity. The compound exhibits excellent stability under standard conditions and facilitates efficient deprotection for downstream applications in medicinal chemistry and catalyst design.

Application

(R)-tert-Butyl 2-aminopropanoate serves as a chiral building block for asymmetric synthesis, enabling efficient access to enantiomerically pure amino acid derivatives and peptidomimetics. Its tert-butyl carbamate group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The molecule exhibits high functional group tolerance and compatibility with standard coupling reactions, making it a reliable scaffold for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1760
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 52.32
LogP 0.6753
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-tert-Butyl 2-aminopropanoate

CAS No. 59624-87-2

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