Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Amino-5-methylbenzonitrile

  • CAS No. 5925-93-9

  • Cat. No. CS-W011090
  • Purity≥98%
  • MDL No.MFCD00267506

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-methylbenzonitrile|CS-W011090

Structure of 5925-93-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5925-93-9
  • Cat. No. CS-W011090
  • Purity ≥98%
  • MDL No. MFCD00267506
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂
  • Molecular Weight 132.17
  • Synonym(s) 6-Amino-m-tolunitrile
  • SMILES N#CC1=CC(C)=CC=C1N

Description

2-Amino-5-methylbenzonitrile features a strategically positioned nitrile group flanked by an amino moiety and a methyl substituent, enabling its use in constructing electron-rich heterocycles. This ortho-substituted aromatic scaffold offers enhanced solubility and stability under standard bench conditions, facilitating efficient coupling reactions in synthetic workflows.

Application

2-Amino-5-methylbenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinoline derivatives, and other heterocyclic scaffolds. Its amino and nitrile groups exhibit complementary reactivity, allowing for sequential functionalization under mild conditions. The compound demonstrates excellent bench stability and is readily purified by recrystallization or column chromatography, facilitating integration into multi-step synthetic sequences.

Synthesis

  • Route1

    References

    • SENOMYX, INC. Patent: US2008/306053 A1, 2008 ; Location in patent: Page/Page column 60 ;
  • Route2
    • In-stock
      2-Iodo-4-methylaniline|CS-W004684
      29289-13-2
    • null|null
      544-92-3
    • ~80%
    • In-stock
      2-Amino-5-methylbenzonitrile|CS-W011090
      5925-93-9

    References

    • Kurosu, Michio; Lin, Mei-Huey; Kishi, Yoshito Journal of the American Chemical Society, 2004 , vol. 126, # 39 p. 12248 - 12249
  • Route3
    • In-stock
      2-Bromo-4-methylaniline|CS-W007636
      583-68-6
    • null|null
      544-92-3
    • ~61%
    • In-stock
      2-Amino-5-methylbenzonitrile|CS-W011090
      5925-93-9

    References

    • ELI LILLY AND COMPANY Patent: WO2004/14895 A1, 2004 ; Location in patent: Page 61 ; WO 2004/014895 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   49.81
  • LogP   1.4489
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Amino-5-methylbenzonitrile sigma2-Amino-5-methylbenzonitrile manufacturer2-Amino-5-methylbenzonitrile price2-Amino-5-methylbenzonitrile structure2-Amino-5-methylbenzonitrile SDSbuy 2-Amino-5-methylbenzonitrile2-Amino-5-methylbenzonitrile supplier2-Amino-5-methylbenzonitrile uses2-Amino-5-methylbenzonitrile molecular weightprice of 2-Amino-5-methylbenzonitrile2-Amino-5-methylbenzonitrile chemical name formula of 2-Amino-5-methylbenzonitrile
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label