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CS-W001157 4
Total: USD 88.00

rel-(2R,6S)-Piperidine-2,6-dicarboxylic acid

  • CAS No. 59234-40-1

  • Cat. No. CS-0132152
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

rel-(2R,6S)-Piperidine-2,6-dicarboxylic acid|CS-0132152

Structure of 59234-40-1

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General Information

  • CAS No. 59234-40-1
  • Cat. No. CS-0132152
  • Purity ≥97%
  • MDL No. None
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁NO₄
  • Molecular Weight 173.17
  • Synonym(s) CIS-2,6-PIPERIDINE DICARBOXYLIC ACID
  • SMILES O=C([C@@H]1N[C@H](C(O)=O)CCC1)O

Description

rel-(2R,6S)-Piperidine-2,6-dicarboxylic acid is a stereochemically defined piperidine scaffold featuring two carboxylic acid groups at the 2 and 6 positions. This configuration imparts distinct conformational rigidity and polarity, enabling its use as a key building block in the synthesis of bioactive molecules and peptidomimetics. The molecule demonstrates enhanced solubility and stability under standard bench conditions.

Application

rel-(2R,6S)-Piperidine-2,6-dicarboxylic acid serves as a stereochemically defined building block for the synthesis of bioactive heterocycles and peptidomimetics. Its rigid, chiral piperidine core enables precise control over molecular conformation in medicinal chemistry applications. The dicarboxylic acid functionality offers versatile handles for derivatization, including amide coupling and salt formation, while maintaining bench stability and compatibility with standard purification techniques.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   86.63
  • LogP   -0.3337
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

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