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CS-W001157 4
Total: USD 88.00

3,3-Dimethylmorpholine

  • CAS No. 59229-63-9

  • Cat. No. CS-0094495
  • Molecule weight115.17
  • Purity≥97%
  • MDL No.MFCD09608072

*For research and further manufacturing use only, not for direct human use.

3,3-Dimethylmorpholine|CS-0094495

Structure of 59229-63-9

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General Information

  • CAS No. 59229-63-9
  • Cat. No. CS-0094495
  • Purity ≥97%
  • MDL No. MFCD09608072
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) 3,3-Dimethylmorpholine HCl
  • SMILES CC1(C)NCCOC1

Description

3,3-Dimethylmorpholine is a sterically hindered, bench-stable nitrogen heterocycle featuring a tertiary amine center. This morpholine derivative exhibits enhanced solubility in organic media and resists oxidation under standard conditions. Its rigid, electron-rich structure facilitates use in catalysis and as a building block for bioactive molecules.

Application

3,3-Dimethylmorpholine serves as a stable, sterically hindered nitrogen heterocycle that functions as a versatile building block in synthetic organic chemistry. Its tertiary amine center enables efficient alkylation and quaternization reactions, while the dimethyl substitution enhances resistance to oxidation and hydrolysis. The compound facilitates smooth coupling processes and acts as a valuable scaffold in medicinal chemistry due to its favorable solubility and metabolic stability.

Synthesis

  • Route1
    • 2-((2-Hydroxyethyl)amino)-2-methylpropan-1-ol|CS-0968935
      70787-40-5
    • ~%
    • In-stock
      3,3-Dimethylmorpholine|CS-0094495
      59229-63-9

    References

    • Journal of Organic Chemistry, , vol. 11, p. 289

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   0.3848
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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