2-Chloro-N,N-dimethylpyridin-4-amine

Name: 2-Chloro-N,N-dimethylpyridin-4-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 59047-70-0
Cat. No. CS-W001602
Purity≥98%
MDL No.MFCD09031034

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-N,N-dimethylpyridin-4-amine|CS-W001602

Structure of 59047-70-0

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 59047-70-0
Cat. No. CS-W001602
Purity ≥98%
MDL No. MFCD09031034
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₉ClN₂
Molecular Weight 156.61
Synonym(s) 2-Chloro-4-(dimethylamino)pyridine
SMILES CN(C1=CC(Cl)=NC=C1)C

Description

2-Chloro-N,N-dimethylpyridin-4-amine features a pyridine core with a chloro group at the 2-position and N,N-dimethyl substitution at the 4-position, delivering enhanced electrophilicity and stability. This configuration enables efficient coupling in cross-coupling reactions and facilitates incorporation into functionalized heterocycles under mild conditions.

Application

2-Chloro-N,N-dimethylpyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The chloropyridine moiety exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the dimethylamino group enhances solubility and modulates electronic properties. Bench-stable and readily purified by column chromatography, it functions as a key intermediate in the synthesis of heterocyclic scaffolds relevant to pharmaceutical development.

Synthesis

Route1
- 1122-58-3
- ~87%
- In-stock
  
  59047-70-0
References
- Cuperly, David; Gros, Philippe; Fort, Yves Journal of Organic Chemistry, 2002 , vol. 67, # 1 p. 238 - 241
Route2
- In-stock
  
  26452-80-2
- 124-40-3
- ~88%
- In-stock
  
  59047-70-0
References
- Schlosser, Manfred; Bobbio, Carla; Rausis, Thierry Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2494 - 2502
Route3
- In-stock
  
  26452-80-2
- 124-40-3
- ~%
- In-stock
  
  59047-70-0
- In-stock
  
  735255-56-8
References
- KALYPSYS, INC. Patent: WO2009/29617 A1, 2009 ; Location in patent: Page/Page column 47 ; WO 2009/029617 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 16.13
LogP 1.801
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Chloro-N,N-dimethylpyridin-4-amine sigma2-Chloro-N,N-dimethylpyridin-4-amine manufacturer2-Chloro-N,N-dimethylpyridin-4-amine price2-Chloro-N,N-dimethylpyridin-4-amine structure2-Chloro-N,N-dimethylpyridin-4-amine SDSbuy 2-Chloro-N,N-dimethylpyridin-4-amine2-Chloro-N,N-dimethylpyridin-4-amine supplier2-Chloro-N,N-dimethylpyridin-4-amine uses2-Chloro-N,N-dimethylpyridin-4-amine molecular weightprice of 2-Chloro-N,N-dimethylpyridin-4-amine2-Chloro-N,N-dimethylpyridin-4-amine chemical name formula of 2-Chloro-N,N-dimethylpyridin-4-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-N,N-dimethylpyridin-4-amine

CAS No. 59047-70-0

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words