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CS-W001157 4
Total: USD 88.00

4-(4-Fluorophenyl)butanoic acid

  • CAS No. 589-06-0

  • Cat. No. CS-0022368
  • Purity≥97%
  • MDL No.MFCD03788503
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(4-Fluorophenyl)butanoic acid|CS-0022368

Structure of 589-06-0

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Description

4-(4-Fluorophenyl)butanoic acid features a conjugated aryl-aliphatic linkage with a fluorinated phenyl moiety, delivering enhanced metabolic stability and favorable lipophilicity. This structure integrates readily into bioactive scaffolds, serving as a key building block in medicinal chemistry for modulating pharmacokinetic properties.

Application

4-(4-Fluorophenyl)butanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard coupling and functionalization reactions. Its fluorinated aryl group enhances metabolic stability and modulates electronic properties, while the aliphatic carboxylic acid facilitates derivatization via amide, ester, or amidation protocols. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows in API development.

General Information

  • CAS No. 589-06-0
  • Cat. No. CS-0022368
  • Purity ≥97%
  • MDL No. MFCD03788503
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁FO₂
  • Molecular Weight 182.19
  • Synonym(s) 4-Fluorobenzenebutanoic acid; 4-(p-fluorophenyl)butyric acid
  • SMILES O=C(O)CCCC1=CC=C(F)C=C1

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.233
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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