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Structure of 459-31-4
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3-(4-Fluorophenyl)propanoic acid is a fluorinated aromatic carboxylic acid featuring a conjugated phenyl-propionic acid scaffold. This compound serves as a key building block in medicinal chemistry, integrating readily into bioactive molecules through amide or ester linkages. The para-fluoro substitution enhances metabolic stability and modulates electronic properties, improving target affinity. Its bench-stable nature supports reliable handling in synthetic workflows.
3-(4-Fluorophenyl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard functional group transformations. Its fluorinated aryl moiety enhances metabolic stability and membrane permeability, while the carboxylic acid group facilitates coupling reactions, esterification, and amide formation. The compound exhibits excellent bench stability and is compatible with common purification methods, making it a reliable intermediate for API development and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: