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Structure of 58808-59-6
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4-(2,2,2-Trifluoroacetyl)benzoic acid features a trifluoromethyl ketone group positioned para to a carboxylic acid on a benzene ring, enabling direct conjugation with nucleophiles or incorporation into bioactive scaffolds. This electron-deficient aryl ketone facilitates efficient Michael additions and serves as a key intermediate in medicinal chemistry for building fluorinated heterocycles under mild conditions.
4-(2,2,2-Trifluoroacetyl)benzoic acid serves as a versatile building block in medicinal chemistry and synthetic organic research. Its trifluoromethyl ketone group enables efficient Michael additions, nucleophilic acyl substitutions, and heterocycle formation under mild conditions. The molecule exhibits good bench stability and facilitates straightforward purification via recrystallization or column chromatography. Functions effectively in the construction of fluorinated aromatic scaffolds relevant to API development and bioactive compound synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: