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CS-W001157 4
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tert-Butyl 2-iodoacetate

  • CAS No. 49827-15-8

  • Cat. No. CS-W022991
  • Purity≥96%
  • MDL No.MFCD09833728

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 2-iodoacetate|CS-W022991

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General Information

  • CAS No. 49827-15-8
  • Cat. No. CS-W022991
  • Purity ≥96%
  • MDL No. MFCD09833728
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁IO₂
  • Molecular Weight 242.06
  • Synonym(s) tert-Butyl Iodoacetate
  • SMILES O=C(OC(C)(C)C)CI

Description

tert-Butyl 2-iodoacetate delivers a reactive iodoacetyl group for selective conjugation in chemical biology and peptide modification. This bench-stable ester integrates readily into functionalized scaffolds, enabling efficient coupling under mild conditions. The tert-butyl moiety enhances solubility and stability during storage and handling.

Application

tert-Butyl 2-iodoacetate serves as a versatile iodinated building block for C–C bond formation, enabling efficient alkylation of enolates and nucleophiles under mild conditions. Its stability under ambient storage and compatibility with diverse functional groups facilitate straightforward purification and integration into multi-step syntheses. Functions as a key reagent in the construction of α-iodo carbonyl derivatives and heterocyclic scaffolds via halogen-assisted cyclizations.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301-H311+H331-H315-H319-H335
Precautionary Statements : P210-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.7631
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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