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CS-W001157 4
Total: USD 88.00

1H-Imidazole-4-sulfonyl chloride

  • CAS No. 58767-51-4

  • Cat. No. CS-W010803
  • Molecule weight166.58
  • Purity≥97%
  • MDL No.MFCD08687938

*For research and further manufacturing use only, not for direct human use.

1H-Imidazole-4-sulfonyl chloride|CS-W010803

Structure of 58767-51-4

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General Information

  • CAS No. 58767-51-4
  • Cat. No. CS-W010803
  • Purity ≥97%
  • MDL No. MFCD08687938
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃ClN₂O₂S
  • Molecular Weight 166.58
  • Synonym(s) 4-Chlorosulfonylimidazole
  • SMILES ClS(=O)(=O)C1=CNC=N1

Description

N-(2-(2-Aminoethoxy)ethyl)-2-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide is an E3 ligase ligand-linker conjugate used in PROTAC dTAG-13 as a degrader of FKBP12, F36V, and BET proteins.

Synthesis

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    • 1H-Imidazole-4-sulfonyl chloride|CS-W010803
      58767-51-4

    References

    • Eerland, Martijn F.; Hedberg, Christian Journal of Organic Chemistry, 2012 , vol. 77, # 4 p. 2047 - 2052

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   62.82
  • LogP   0.3372
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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