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CS-W001157 4
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3-Chloropropionamide

  • CAS No. 5875-24-1

  • Cat. No. CS-0204808
  • Purity≥98%
  • MDL No.MFCD00008040

*For research and further manufacturing use only, not for direct human use.

3-Chloropropionamide|CS-0204808

Structure of 5875-24-1

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General Information

  • CAS No. 5875-24-1
  • Cat. No. CS-0204808
  • Purity ≥98%
  • MDL No. MFCD00008040
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆ClNO
  • Molecular Weight 107.54
  • Synonym(s) 3-chloro-propanamide
  • SMILES O=C(N)CCCl

Description

3-Chloropropionamide was used as alkylating agent in the synthesis of 1-(2-carbamoyl-ethyl)indole-3-acetic acid.

Application

3-Chloropropionamide serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds and bioactive molecules. Its reactive chloro group facilitates nucleophilic substitution, while the amide functionality offers stability and compatibility with diverse reaction conditions. The compound exhibits bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

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      3-Chloropropionamide|CS-0204808
      5875-24-1

    References

    • US2012/190879 A1, ; Page/Page column 5 ;
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      3-Chloropropionamide|CS-0204808
      5875-24-1

    References

    • Tetrahedron, , vol. 21, p. 2453 - 2467
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    References

    • Chemical & Pharmaceutical Bulletin, , vol. 36, # 8 p. 3125 - 3129

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H411
Precautionary Statements : P264-P270-P273-P330-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.09
  • LogP   0.1006
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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