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CS-W001157 4
Total: USD 88.00

2-Bromoterephthalic acid

  • CAS No. 586-35-6

  • Cat. No. CS-W012728
  • Purity≥96%
  • MDL No.MFCD00002403

*For research and further manufacturing use only, not for direct human use.

2-Bromoterephthalic acid|CS-W012728

Structure of 586-35-6

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General Information

  • CAS No. 586-35-6
  • Cat. No. CS-W012728
  • Purity ≥96%
  • MDL No. MFCD00002403
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrO₄
  • Molecular Weight 245.03
  • Synonym(s) 2-Bromobenzene-1,4-dicarboxylic acid
  • SMILES O=C(O)C1=CC=C(C(=O)O)C(Br)=C1

Description

2-Bromoterephthalic acid features a bromine substituent at the para position relative to one carboxylic acid group, enabling selective functionalization in aromatic coupling reactions. This electron-deficient diacid scaffold integrates readily into polymer backbones and serves as a key intermediate for bioconjugation and metal-organic framework synthesis under standard conditions.

Application

2-Bromoterephthalic acid serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of functionalized aromatic systems. Its bromo and carboxylic acid functionalities provide orthogonal reactivity, facilitating sequential transformations in complex molecule synthesis. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for use in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   1.8455
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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