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CS-W001157 4
Total: USD 88.00

4'-Hydroxy-[1,1'-biphenyl]-4-carboxylic acid

  • CAS No. 58574-03-1

  • Cat. No. CS-0012227
  • Purity≥96%
  • MDL No.MFCD00059078

*For research and further manufacturing use only, not for direct human use.

4'-Hydroxy-[1,1'-biphenyl]-4-carboxylic acid|CS-0012227

Structure of 58574-03-1

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General Information

  • CAS No. 58574-03-1
  • Cat. No. CS-0012227
  • Purity ≥96%
  • MDL No. MFCD00059078
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₀O₃
  • Molecular Weight 214.22
  • Synonym(s) 4-hydroxybiphenyl-4'-carboxylic acid
  • SMILES O=C(C1=CC=C(C2=CC=C(O)C=C2)C=C1)O

Application

4'-Hydroxy-[1,1'-biphenyl]-4-carboxylic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at both the phenolic and carboxylic acid termini. Its dual functionality facilitates coupling reactions, including amide formation and esterification, with excellent bench stability and straightforward purification. The molecule functions as a key scaffold for bioactive heterocycles and conjugated systems, offering high compatibility in standard synthetic workflows.

Synthesis

  • Route1

    References

    • Kawabata, Kohsuke; Takeguchi, Masaki; Goto, Hiromasa Macromolecules, 2013 , vol. 46, # 6 p. 2078 - 2091
  • Route2
    • null|null
      106-41-2
    • In-stock
      4-Boronobenzoic acid|CS-W019665
      14047-29-1
    • ~88%
    • In-stock
      4'-Hydroxy-[1,1'-biphenyl]-4-carboxylic acid|CS-0012227
      58574-03-1

    References

    • Maity, Indrajit; Rasale, Dnyaneshwar B.; Das, Apurba K. RSC Advances, 2014 , vol. 4, # 6 p. 2984 - 2988
  • Route3

    References

    • The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland Defence Evaluation Research Agency Patent: US6337420 B1, 2002 ; Location in patent: Page column 6 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   2.7574
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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