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CS-W001157 4
Total: USD 88.00

2-Isopropyl-1h-benzimidazole

  • CAS No. 5851-43-4

  • Cat. No. CS-0117015
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Isopropyl-1h-benzimidazole|CS-0117015

Structure of 5851-43-4

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General Information

  • CAS No. 5851-43-4
  • Cat. No. CS-0117015
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂
  • Molecular Weight 160.22
  • Synonym(s) 2-Isopropylbenzimidazole
  • SMILES CC(C1=NC2=CC=CC=C2N1)C

Description

2-Isopropyl-1H-benzimidazole features a benzimidazole core with a sterically hindered isopropyl group at the 2-position, enhancing its stability and solubility in organic media. This substitution pattern imparts favorable electronic properties for use in catalytic systems and pharmaceutical intermediates. The molecule exhibits bench-stable handling characteristics under standard conditions.

Application

2-Isopropyl-1H-benzimidazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard functionalization protocols. Its bench-stable nature and tolerance to diverse reaction conditions facilitate straightforward derivatization, making it well-suited for modular synthesis of pharmaceutical intermediates and target compounds.

Synthesis

  • Route1
    • null|null
      6321-40-0
    • null|null
      95-54-5
    • ~84%
    • In-stock
      2-Isopropyl-1h-benzimidazole|CS-0117015
      5851-43-4

    References

    • Tran, Ngoc Thang; Cho, Chan Sik Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 12 p. 4188 - 4190
  • Route2
    • null|null
      95-54-5
    • null|null
      79-31-2
    • ~75%
    • In-stock
      2-Isopropyl-1h-benzimidazole|CS-0117015
      5851-43-4

    References

    • Karuvalam, Ranjith P.; Haridas, Karickal R.; Shetty, Suchetha N. Journal of the Chilean Chemical Society, 2012 , vol. 57, # 2 p. 1122 - 1125,4
  • Route3
    • null|null
      1116-40-1
    • null|null
      95-54-5
    • ~73%
    • In-stock
      2-Isopropyl-1h-benzimidazole|CS-0117015
      5851-43-4

    References

    • Tran, Ngoc Thang; Cho, Chan Sik Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 12 p. 4188 - 4190

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.6863
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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