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CS-W001157 4
Total: USD 88.00

Furan-2,5-dicarbonitrile

  • CAS No. 58491-62-6

  • Cat. No. CS-0157892
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Furan-2,5-dicarbonitrile|CS-0157892

Structure of 58491-62-6

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General Information

  • CAS No. 58491-62-6
  • Cat. No. CS-0157892
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₂N₂O
  • Molecular Weight 118.09
  • Synonym(s) 2,5-Furandicarbonitrile
  • SMILES C1=C(C#N)OC(=C1)C#N

Description

Furan-2,5-dicarbonitrile features a rigid furan core flanked by electron-deficient nitrile groups, enabling efficient integration into π-conjugated systems. This bifunctional scaffold supports modular synthesis of heterocyclic architectures and serves as a key building block in materials chemistry.

Application

Furan-2,5-dicarbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted furan derivatives via nucleophilic addition and cycloaddition reactions. Its dual nitrile groups enhance reactivity in transition-metal-catalyzed couplings and facilitate functionalization under mild conditions. The molecule exhibits excellent bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • 2,5-Furandicarboxylic acid,99.99%|CS-1709659
      3238-40-2
    • ~24%
    • In-stock
      Furan-2,5-dicarbonitrile|CS-0157892
      58491-62-6

    References

    • RHODIA OPERATIONS; Marion, Philippe; Jacquot, Roland Patent: US2014/171663 A1, 2014 ; Location in patent: Paragraph 0050 ;
  • Route2
    • Furan-2,5-dicarboxamide|CS-0937294
      124052-68-2
    • ~%
    • In-stock
      Furan-2,5-dicarbonitrile|CS-0157892
      58491-62-6

    References

    • Phrix-Werke Patent: DE912344 , 1952 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H315-H319-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   60.72
  • LogP   1.02296
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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