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CS-W001157 4
Total: USD 88.00

1-(2-Bromoethyl)-4-methylpiperazine dihydrobromide

  • CAS No. 5845-28-3

  • Cat. No. CS-0052912
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(2-Bromoethyl)-4-methylpiperazine dihydrobromide|CS-0052912

Structure of 5845-28-3

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General Information

  • CAS No. 5845-28-3
  • Cat. No. CS-0052912
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₇Br₃N₂
  • Molecular Weight 368.94
  • Synonym(s) Piperazine, 1-(2-bromoethyl)-4-methyl-, hydrobromide
  • SMILES Br.Br.CN1CCN(CCBr)CC1

Description

1-(2-Bromoethyl)-4-methylpiperazine dihydrobromide is a reactive bifunctional building block featuring a primary bromoalkyl group and a tertiary amine site. This combination enables efficient conjugation in synthetic workflows, particularly for linker development in bioconjugation and medicinal chemistry. The dihydrobromide salt form enhances solubility and handling stability under standard conditions.

Application

1-(2-Bromoethyl)-4-methylpiperazine dihydrobromide serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of nitrogen-containing heterocycles and side chains. The bromoethyl handle facilitates nucleophilic substitution reactions, while the piperazine core offers tunable basicity and solubility. Its stability under standard bench conditions and compatibility with diverse functional groups make it well-suited for modular synthesis workflows in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   6.48
  • LogP   1.7845
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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