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Structure of 58381-05-8
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5-Fluoro-2-methoxypyridin-4-amine features a strategically positioned fluorine atom and methoxy group on the pyridine ring, enhancing electron-withdrawing character and enabling selective functionalization. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, serving as a key building block for kinase inhibitors and bioactive nitrogen-containing compounds under standard coupling conditions.
5-Fluoro-2-methoxypyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based pharmacophores. Its fluorine and amine functionalities facilitate downstream coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig couplings, while the methoxy group provides orthogonal reactivity and enhanced solubility. Bench-stable and readily purified, it supports scalable synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: