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CS-W001157 4
Total: USD 88.00

4-Methyl-5-nitropyridine-2-carboxylic acid

  • CAS No. 5832-43-9

  • Cat. No. CS-0035979
  • Molecule weight182.13
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Methyl-5-nitropyridine-2-carboxylic acid|CS-0035979

Structure of 5832-43-9

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General Information

  • CAS No. 5832-43-9
  • Cat. No. CS-0035979
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₂O₄
  • Molecular Weight 182.13
  • Synonym(s) 4-Methyl-5-nitro-2-pyridinecarboxylic acid
  • SMILES CC1=C(C=NC(=C1)C(=O)O)[N+](=O)[O-]

Description

4-Methyl-5-nitropyridine-2-carboxylic acid features a conjugated pyridine core bearing a methyl group at the 4-position, a nitro substituent at the 5-position, and a carboxylic acid at the 2-position. This electron-deficient scaffold integrates readily into heterocyclic syntheses, serving as a key building block for bioactive molecules and functional materials.

Application

4-Methyl-5-nitropyridine-2-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the pyridine ring due to orthogonal reactivity of the nitro and carboxylic acid groups. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient access to substituted pyridine scaffolds relevant to medicinal chemistry and agrochemical development.

Synthesis

  • Route1
    • 4-Methyl-5-nitropyridine-2-carbaldehyde|CS-0056700
      5832-38-2
    • ~95%
    • In-stock
      4-Methyl-5-nitropyridine-2-carboxylic acid|CS-0035979
      5832-43-9

    References

    • Synthesis, , # 3 p. 295 - 297

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   93.33
  • LogP   0.99642
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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