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(4S,4'S)-2,2'-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-(phenylmethyl)oxazole]

  • CAS No. 583058-02-0

  • Cat. No. CS-0097877
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4S,4'S)-2,2'-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-(phenylmethyl)oxazole]|CS-0097877

Structure of 583058-02-0

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General Information

  • CAS No. 583058-02-0
  • Cat. No. CS-0097877
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₅H₃₄N₂O₂
  • Molecular Weight 514.66
  • Synonym(s) (4S,4'S)-2,2'-[2-phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-(phenylmethyl)-Oxazole
  • SMILES C1(C(CC2=CC=CC=C2)(C3=N[C@@H](CC4=CC=CC=C4)CO3)CC5=CC=CC=C5)=N[C@@H](CC6=CC=CC=C6)CO1

Description

This chiral bis-oxazole scaffold features a rigid, sterically defined architecture with two phenylmethyl-substituted oxazole rings linked via a diarylalkylidene bridge. Designed for asymmetric synthesis, it integrates seamlessly into catalytic systems and molecular scaffolds requiring precise spatial control and enhanced stability under standard reaction conditions.

Application

(4S,4'S)-2,2'-[2-Phenyl-1-(phenylmethyl)ethylidene]bis[4,5-dihydro-4-(phenylmethyl)oxazole] serves as a chiral bis-oxazole scaffold with defined stereochemistry, enabling the construction of complex heterocyclic architectures. Its bench-stable, functional group-tolerant structure facilitates use in asymmetric synthesis and transition metal-catalyzed coupling reactions. The molecule functions effectively as a ligand precursor or building block in medicinal chemistry campaigns requiring rigid, stereocontrolled frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   6.5382
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   10

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