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CS-W001157 4
Total: USD 88.00

4-(P-tolyl)piperidin-4-ol

  • CAS No. 57988-60-0

  • Cat. No. CS-0453837
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(P-tolyl)piperidin-4-ol|CS-0453837

Structure of 57988-60-0

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General Information

  • CAS No. 57988-60-0
  • Cat. No. CS-0453837
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO
  • Molecular Weight 191.27
  • Synonym(s) 4-Hydroxy-4-(4-methylphenyl)piperidine Hydrochloride
  • SMILES CC1=CC=C(C=C1)C2(CCNCC2)O

Synthesis

  • Route1
    • Tert-butyl 4-hydroxy-4-(4-methylphenyl)piperidine-1-carboxylate|CS-0772499
      1260882-14-1
    • ~40%
    • 4-(P-tolyl)piperidin-4-ol|CS-0453837
      57988-60-0

    References

    • Chen, Gang; Xia, Hongguang; Cai, Yu; Ma, Dawei; Yuan, Junying; Yuan, Chengye Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 234 - 239
  • Route2
    • null|null
      13299-35-9
    • ~57%
    • 4-(P-tolyl)piperidin-4-ol|CS-0453837
      57988-60-0

    References

    • Lyles-Eggleston; Margaret; McCollough; Craig; Fan; Pingchen; Ablordeppey; Mardenborough, Joy H.; Leroy; Seth; Borne Medicinal Chemistry Research, 1999 , vol. 9, # 9 p. 686 - 695
  • Route3
    • null|null
      13299-35-9
    • null|null
      7440-05-3
    • ~%
    • 4-(P-tolyl)piperidin-4-ol|CS-0453837
      57988-60-0

    References

    • US4188396 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   1.56602
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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