Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-4-bromobenzaldehyde

  • CAS No. 57848-46-1

  • Cat. No. CS-W008610
  • Purity≥98%
  • MDL No.MFCD00143261

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-bromobenzaldehyde|CS-W008610

Structure of 57848-46-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 57848-46-1
  • Cat. No. CS-W008610
  • Purity ≥98%
  • MDL No. MFCD00143261
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO
  • Molecular Weight 203.01
  • Synonym(s) 4-Bromo-2-fluorobenzaldehyde
  • SMILES O=CC1=CC=C(Br)C=C1F

Description

2-Fluoro-4-bromobenzaldehyde features a fluorine atom at the ortho position and a bromine substituent at the para position relative to the aldehyde group. This electron-deficient aromatic scaffold enables efficient coupling in cross-coupling reactions, particularly Suzuki-Miyaura and Stille transformations. The molecule exhibits enhanced stability under standard bench conditions and integrates readily into complex molecular architectures.

Application

2-Fluoro-4-bromobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct introduction of fluorine and bromine substituents adjacent to an aldehyde group. Its reactivity facilitates nucleophilic additions, coupling reactions, and heterocycle formation under standard conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, simplifying purification and downstream functionalization.

Synthesis

  • Route1

    References

    • ANTHEM BIOSCIENCES PRIVATE LIMITED Patent: US2012/101099 A1, 2012 ; Location in patent: Page/Page column 13; 14 ;
  • Route2
    • In-stock
      1,4-Dibromo-2-fluorobenzene|CS-W008202
      1435-52-5
    • null|null
      68-12-2
    • ~90%
    • In-stock
      2-Fluoro-4-bromobenzaldehyde|CS-W008610
      57848-46-1

    References

    • Iida, Takehiko; Wada, Toshihiro; Tomimoto, Koji; Mase, Toshiaki Tetrahedron Letters, 2001 , vol. 42, # 29 p. 4841 - 4844
  • Route3
    • null|null
      877129-98-1
    • ~51%
    • In-stock
      2-Fluoro-4-bromobenzaldehyde|CS-W008610
      57848-46-1

    References

    • Wang, Guangjun; Li, Zhengwei; Ha, Chengyong; Ding, Ke Synthetic Communications, 2008 , vol. 38, # 10 p. 1629 - 1637

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.4007
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Fluoro-4-bromobenzaldehyde sigma2-Fluoro-4-bromobenzaldehyde manufacturer2-Fluoro-4-bromobenzaldehyde price2-Fluoro-4-bromobenzaldehyde structure2-Fluoro-4-bromobenzaldehyde SDSbuy 2-Fluoro-4-bromobenzaldehyde2-Fluoro-4-bromobenzaldehyde supplier2-Fluoro-4-bromobenzaldehyde uses2-Fluoro-4-bromobenzaldehyde molecular weightprice of 2-Fluoro-4-bromobenzaldehyde2-Fluoro-4-bromobenzaldehyde chemical name formula of 2-Fluoro-4-bromobenzaldehyde
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label