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CS-W001157 4
Total: USD 88.00

2-Fluoro-4-bromobenzoic acid

  • CAS No. 112704-79-7

  • Cat. No. CS-M3187
  • Purity≥98%
  • MDL No.MFCD00143263

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-bromobenzoic acid|CS-M3187

Structure of 112704-79-7

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General Information

  • CAS No. 112704-79-7
  • Cat. No. CS-M3187
  • Purity ≥98%
  • MDL No. MFCD00143263
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrFO₂
  • Molecular Weight 219.01
  • Synonym(s) 4-Bromo-2-fluorobenzoic acid; NSC 190364; 4-BroMo-2-fluorobenzoic acid 5GR
  • SMILES O=C(O)C1=CC=C(Br)C=C1F

Description

4-Bromo-2-fluorobenzoic acid is a halogen substituted benzoic acid.4-Bromo-2-fluorobenzoic acid may be used in the synthesis of biaryl intermediates by palladium-mediated coupling with various aryl boronic acids.

Synthesis

  • Route1

    References

    • Yang, Fan; Sun, Jing; Zheng, Rui; Qiu, Wenwei; Tang, Jie; He, Mingyuan Tetrahedron, 2004 , vol. 60, # 5 p. 1225 - 1228
  • Route2
    • null|null
      124-38-9
    • In-stock
      1,4-Dibromo-2-fluorobenzene|CS-W008202
      1435-52-5
    • ~90%
    • In-stock
      2-Fluoro-4-bromobenzoic acid|CS-M3187
      112704-79-7

    References

    • Heiss, Christophe; Leroux, Frederic; Schlosser, Manfred European Journal of Organic Chemistry, 2005 , # 24 p. 5242 - 5247
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 2 p. 748 - 759

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.2864
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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