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CS-W001157 4
Total: USD 88.00

6-Bromo-2-naphthalenecarboxylic acid

  • CAS No. 5773-80-8

  • Cat. No. CS-W009021
  • Purity≥95%
  • MDL No.MFCD01075720

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-naphthalenecarboxylic acid|CS-W009021

Structure of 5773-80-8

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General Information

  • CAS No. 5773-80-8
  • Cat. No. CS-W009021
  • Purity ≥95%
  • MDL No. MFCD01075720
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇BrO₂
  • Molecular Weight 251.08
  • Synonym(s) None
  • SMILES O=C(C1=CC=C2C=C(Br)C=CC2=C1)O

Description

6-Bromo-2-naphthylacetic acid features a bromine substituent at the 6-position of the naphthalene core, enhancing electrophilic reactivity and enabling downstream functionalization. The carboxylic acid group provides polarity and facilitates conjugation or derivatization under mild conditions. This structure supports applications in synthetic organic chemistry and materials science where controlled reactivity and solubility are critical.

Application

6-Bromo-2-naphthylacetic acid serves as a versatile building block for the synthesis of naphthalene-based pharmaceutical intermediates and functionalized heterocycles. Its brominated aromatic ring enables palladium-catalyzed coupling reactions, while the carboxylic acid group facilitates direct derivatization or salt formation. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   3.3005
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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