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CS-W001157 4
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Bromo-PEG2-alcohol

  • CAS No. 57641-66-4

  • Cat. No. CS-0114928
  • Purity≥97%
  • MDL No.MFCD20621572

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG2-alcohol|CS-0114928

Structure of 57641-66-4

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General Information

  • CAS No. 57641-66-4
  • Cat. No. CS-0114928
  • Purity ≥97%
  • MDL No. MFCD20621572
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉BrO₂
  • Molecular Weight 169.02
  • Synonym(s) None
  • SMILES BrCCOCCO

Description

Bromo-PEG2-alcohol features a reactive bromide terminus flanked by a short, hydrophilic PEG spacer and a terminal hydroxyl group. This bifunctional architecture enables site-specific conjugation in aqueous environments while maintaining solubility and stability under standard conditions. Ideal for modular synthesis of bioconjugates and functionalized materials.

Application

Bromo-PEG2-alcohol serves as a versatile bifunctional linker for conjugation and polymer synthesis. The bromo group enables efficient nucleophilic substitution with amines or thiols, while the terminal hydroxyl facilitates further derivatization or purification via standard chromatography. Its two-ethylene glycol unit spacer provides enhanced solubility and stability in aqueous and organic media, making it ideal for bioconjugation, peptide modification, and functionalized material development.

Synthesis

  • Route1

    References

    • An, Haoyun; Bradshaw, Jerald S.; Krakowiak, Krzysztof E.; Tarbet, Bryon J.; Dalley, N. Kent; et al. Journal of Organic Chemistry, 1993 , vol. 58, # 27 p. 7694 - 7699
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      Bromo-PEG2-alcohol|CS-0114928
      57641-66-4

    References

    • DE670419 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 865
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      Br-PEG3-OH|CS-0109578
      57641-67-5
    • In-stock
      Bromo-PEG2-alcohol|CS-0114928
      57641-66-4

    References

    • DE670419 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 867

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.3902
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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