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CS-W001157 4
Total: USD 88.00

Bromo-PEG1-CH2COOH

  • CAS No. 1135131-50-8

  • Cat. No. CS-0105329
  • Purity≥97%
  • MDL No.MFCD20637665

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG1-CH2COOH|CS-0105329

Structure of 1135131-50-8

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General Information

  • CAS No. 1135131-50-8
  • Cat. No. CS-0105329
  • Purity ≥97%
  • MDL No. MFCD20637665
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BrO₃
  • Molecular Weight 183.00
  • Synonym(s) None
  • SMILES OC(COCCBr)=O

Description

Bromo-PEG1-CH2COOH features a reactive bromo group flanked by a short PEG spacer and a carboxylic acid terminus. This bifunctional architecture enables site-specific conjugation in bioconjugation workflows, combining efficient coupling chemistry with enhanced solubility in aqueous systems.

Application

Bromo-PEG1-CH₂COOH serves as a versatile bifunctional linker for conjugation and polymer functionalization. The bromo group enables efficient nucleophilic substitution with amines, while the carboxylic acid facilitates amide coupling or activation via standard reagents. This structure offers excellent bench stability, solubility in aqueous and organic media, and compatibility with diverse synthetic workflows, making it ideal for peptide-protein conjugates, antibody-drug conjugate (ADC) intermediates, and surface-functionalized materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.4825
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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