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CS-W001157 4
Total: USD 88.00

Methyl 2-methyl-2-phenylpropanoate

  • CAS No. 57625-74-8

  • Cat. No. CS-W007095
  • Purity≥97%
  • MDL No.MFCD01846451

*For research and further manufacturing use only, not for direct human use.

Methyl 2-methyl-2-phenylpropanoate|CS-W007095

Structure of 57625-74-8

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General Information

  • CAS No. 57625-74-8
  • Cat. No. CS-W007095
  • Purity ≥97%
  • MDL No. MFCD01846451
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₄O₂
  • Molecular Weight None
  • Synonym(s) Methyl dimethylbenzeneacetate; Methyl 2-methyl-2-phenylpropanoate
  • SMILES CC(C1=CC=CC=C1)(C)C(OC)=O

Description

Methyl 2-methyl-2-phenylpropanoate is a sterically hindered ester featuring a tertiary α-carbon. This structural motif imparts enhanced stability and resistance to hydrolysis under standard conditions. The aromatic phenyl group contributes electron-withdrawing character, modulating reactivity in synthetic transformations. Its bench-stable nature facilitates handling in multi-step syntheses.

Synthesis

  • Route1
    • null|null
      101-41-7
    • null|null
      74-88-4
    • ~85%
    • In-stock
      Methyl 2-methyl-2-phenylpropanoate|CS-W007095
      57625-74-8

    References

    • ABBOTT LABORATORIES Patent: WO2005/19191 A2, 2005 ; Location in patent: Page/Page column 141 ; WO 2005/019191 A2
  • Route2
    • null|null
      108-86-1
    • null|null
      547-63-7
    • ~88%
    • In-stock
      Methyl 2-methyl-2-phenylpropanoate|CS-W007095
      57625-74-8

    References

    • Jorgensen, Morten; Lee, Sunwoo; Liu, Xiaoxiang; Wolkowski, Joanna P.; Hartwig, John F. Journal of the American Chemical Society, 2002 , vol. 124, # 42 p. 12557 - 12565
  • Route3
    • null|null
      67-56-1
    • In-stock
      2-Methyl-2-phenylpropanoic acid|CS-W004146
      826-55-1
    • ~96%
    • In-stock
      Methyl 2-methyl-2-phenylpropanoate|CS-W007095
      57625-74-8

    References

    • Yu, Zhoujie; Wang, Wei; Chen, Liqin Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 7 p. 352 - 356

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   2.1372
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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