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CS-W001157 4
Total: USD 88.00

2,4,6-Trimethylbromobenzene

  • CAS No. 576-83-0

  • Cat. No. CS-W007505
  • Purity≥98%
  • MDL No.MFCD00000073

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethylbromobenzene|CS-W007505

Structure of 576-83-0

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General Information

  • CAS No. 576-83-0
  • Cat. No. CS-W007505
  • Purity ≥98%
  • MDL No. MFCD00000073
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁Br
  • Molecular Weight 199.09
  • Synonym(s) 2-Bromomesitylene
  • SMILES CC1=C(Br)C(C)=CC(C)=C1

Description

2,4,6-Trimethylbromobenzene features a highly sterically hindered aromatic core with three methyl groups positioned ortho and para to the bromine substituent. This configuration imparts exceptional stability and resistance to nucleophilic displacement, enabling reliable use in palladium-catalyzed cross-coupling reactions under standard conditions. The molecule's bench-stable nature simplifies handling and storage in synthetic workflows.

Synthesis

  • Route1
    • null|null
      108-67-8
    • ~98%
    • In-stock
      2,4,6-Trimethylbromobenzene|CS-W007505
      576-83-0

    References

    • Goldberg, Yuri; Alper, Howard Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 3072 - 3075
  • Route2
    • null|null
      108-67-8
    • ~70%
    • In-stock
      2,4,6-Trimethylbromobenzene|CS-W007505
      576-83-0
    • In-stock
      2,4-Dibromo-1,3,5-trimethylbenzene|CS-W010068
      6942-99-0

    References

    • Merck Patent Gesellschaft Patent: US7271302 B1, 2007 ; Location in patent: Page/Page column 5-6 ;
  • Route3
    • null|null
      108-67-8
    • ~10%
    • In-stock
      1-(Bromomethyl)-3,5-dimethylbenzene|CS-W002092
      27129-86-8
    • In-stock
      2,4,6-Trimethylbromobenzene|CS-W007505
      576-83-0

    References

    • Journal of Organic Chemistry, , vol. 63, # 17 p. 6023 - 6026

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H335
Precautionary Statements : P261-P271-P304+P340-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.37436
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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