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CS-W001157 4
Total: USD 88.00

1,3-Dibromo-2,4-dimethylbenzene

  • CAS No. 90434-19-8

  • Cat. No. CS-0061133
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1,3-Dibromo-2,4-dimethylbenzene|CS-0061133

Structure of 90434-19-8

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General Information

  • CAS No. 90434-19-8
  • Cat. No. CS-0061133
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈Br₂
  • Molecular Weight 263.96
  • Synonym(s) Benzene, 1,3-dibromo-2,4-dimethyl-
  • SMILES CC1=C(C(=C(C=C1)Br)C)Br

Description

1,3-Dibromo-2,4-dimethylbenzene features two bromine substituents at meta positions relative to each other, flanked by methyl groups that impart steric shielding. This configuration enhances stability and facilitates selective electrophilic substitution reactions in synthetic organic chemistry workflows.

Application

1,3-Dibromo-2,4-dimethylbenzene serves as a versatile building block in aromatic synthesis, enabling efficient access to substituted benzene derivatives through palladium-catalyzed cross-coupling reactions. The bromine substituents exhibit high reactivity in Suzuki, Stille, and Negishi couplings, while the methyl groups provide steric and electronic modulation. Bench-stable and readily purified by crystallization, it functions reliably in multi-step sequences for heterocycle and functionalized arene construction.

Synthesis

  • Route1
    • null|null
      108-38-3
    • ~%
    • In-stock
      1,5-Dibromo-2,4-dimethylbenzene|CS-0112336
      615-87-2
    • In-stock
      1,3-Dibromo-2,4-dimethylbenzene|CS-0061133
      90434-19-8

    References

    • Jacobsen Chemische Berichte, 1888 , vol. 21, p. 2815
  • Route2
    • null|null
      7664-93-9
    • In-stock
      1,5-Dibromo-2,4-dimethylbenzene|CS-0112336
      615-87-2
    • ~%
    • In-stock
      1,3-Dibromo-2,4-dimethylbenzene|CS-0061133
      90434-19-8

    References

    • Jacobsen Chemische Berichte, 1888 , vol. 21, p. 2815
  • Route3
    • null|null
      7726-95-6
    • null|null
      108-38-3
    • ~%
    • In-stock
      1,3-Dibromo-2,4-dimethylbenzene|CS-0061133
      90434-19-8

    References

    • Jacobsen Chemische Berichte, 1888 , vol. 21, p. 2815

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.82844
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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