Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride

  • CAS No. 57591-61-4

  • Cat. No. CS-W014809
  • Purity≥95%
  • MDL No.MFCD01862152

*For research and further manufacturing use only, not for direct human use.

(R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride|CS-W014809

Structure of 57591-61-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 57591-61-4
  • Cat. No. CS-W014809
  • Purity ≥95%
  • MDL No. MFCD01862152
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂ClNO₃
  • Molecular Weight 217.65
  • Synonym(s) methyl N-(4-hydroxyphenyl)glycinate hydrochloride; (R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride
  • SMILES O=C([C@@H](C1=CC=C(C=C1)O)N)OC.Cl

Description

(R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride is a chiral building block featuring a phenolic hydroxyl group and a bench-stable ammonium salt. This configuration enables direct incorporation into peptide-like scaffolds, where the para-hydroxyphenyl moiety imparts solubility and hydrogen-bonding capacity. The hydrochloride form enhances stability and handling under standard synthetic conditions.

Application

(R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride serves as a chiral building block for synthesizing phenylethanolamine derivatives. Its well-defined stereochemistry and stable hydrochloride salt form facilitate handling and purification. The molecule enables efficient incorporation of both phenolic and amino functionalities in multistep syntheses, supporting applications in medicinal chemistry and API development where precise stereoselectivity and functional group compatibility are essential.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      D-4-Hydroxyphenylglycine|CS-0020117
      22818-40-2
    • ~99%
    • In-stock
      (R)-Methyl 2-amino-2-(4-hydroxyphenyl)acetate hydrochloride|CS-W014809
      57591-61-4

    References

    • Slattery, Catherine N.; O'Keeffe, Sarah; Maguire, Anita R. Tetrahedron Asymmetry, 2013 , vol. 24, # 20 p. 1265 - 1275
  • Route2

    References

    • Mohammat, Mohd Fazli; Najim, Nigar; Mansor, Nurul Shulehaf; Sarman, Sharil; Shaameri, Zurina; Zain, Mazatulikhma Mat; Hamzah, Ahmad Sazali Arkivoc, 2011 , vol. 2011, # 9 p. 429 - 438

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.9868
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 57591-61-4 sigma57591-61-4 manufacturer57591-61-4 price57591-61-4 structure57591-61-4 SDSbuy 57591-61-457591-61-4 supplier57591-61-4 uses57591-61-4 molecular weightprice of 57591-61-457591-61-4 chemical name formula of 57591-61-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label