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CS-W001157 4
Total: USD 88.00

4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid

  • CAS No. 574-92-5

  • Cat. No. CS-0155758
  • Molecule weight257.17
  • Purity≥95%
  • MDL No.MFCD00006771

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid|CS-0155758

Structure of 574-92-5

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General Information

  • CAS No. 574-92-5
  • Cat. No. CS-0155758
  • Purity ≥95%
  • MDL No. MFCD00006771
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₆F₃NO₃
  • Molecular Weight 257.17
  • Synonym(s) 4-HYDROXY-7-TRIFLUOROMETHYL-3-QUINOLINECARBOXYLIC ACID
  • SMILES C1=CC2=C(C=C1C(F)(F)F)NC=C(C2=O)C(=O)O

Synthesis

  • Route1
    • Ethyl 4-hydroxy-7-(trifluoromethyl)quinoline-3-carboxylate|CS-0368607
      391-02-6
    • ~99%
    • 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid|CS-0155758
      574-92-5

    References

    • Garudachari; Isloor, Arun M.; Satyanarayana; Fun, Hoong-Kun; Pavithra; Kulal, Ananda European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 422 - 432
  • Route2
    • null|null
      370-35-4
    • ~%
    • 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid|CS-0155758
      574-92-5

    References

    • Journal of Medicinal Chemistry, , vol. 41, # 25 p. 4918 - 4926
  • Route3
    • null|null
      98-16-8
    • ~%
    • 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carboxylic acid|CS-0155758
      574-92-5

    References

    • Journal of the American Chemical Society, , vol. 69, p. 371,373

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   2.2451
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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