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Structure of 573762-62-6
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5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile features a trifluoromethyl group and a nitrile moiety positioned ortho to a primary amine on a pyridine scaffold. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates, leveraging its polar functional groups for enhanced solubility and reactivity under standard conditions.
5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through standard coupling and cyclization reactions. Its complementary electron-withdrawing trifluoromethyl and nitrile groups enhance regioselectivity in electrophilic substitutions, while the amino functionality permits facile derivatization. The compound exhibits good bench stability and facilitates purification via standard chromatographic methods, supporting scalable applications in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: