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Structure of 573762-57-9
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5-Nitro-3-(trifluoromethyl)picolinonitrile features a trifluoromethyl group and a nitro substituent positioned ortho to a nitrile-bearing pyridine ring, delivering strong electron-withdrawing character. This configuration enhances reactivity in cross-coupling processes and supports incorporation into advanced heterocyclic architectures for medicinal chemistry applications.
5-Nitro-3-(trifluoromethyl)picolinonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized heterocyclic scaffolds. Its trifluoromethyl and nitrile groups provide strong electron-withdrawing character, facilitating nucleophilic substitution and transition-metal-catalyzed coupling reactions. The nitro group allows for selective reduction or further functionalization, while the molecule exhibits good bench stability and ease of purification—making it well-suited for multi-step synthetic sequences and process-scale applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: