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CS-W001157 4
Total: USD 88.00

5,6-Dimethylpyrazin-2(1H)-one

  • CAS No. 57229-36-4

  • Cat. No. CS-0153595
  • Purity≥97%
  • MDL No.MFCD13705420

*For research and further manufacturing use only, not for direct human use.

5,6-Dimethylpyrazin-2(1H)-one|CS-0153595

Structure of 57229-36-4

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General Information

  • CAS No. 57229-36-4
  • Cat. No. CS-0153595
  • Purity ≥97%
  • MDL No. MFCD13705420
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) 5,6-diMethylpyrazin-2-ol
  • SMILES CC1=C(C)NC(=O)C=N1

Description

5,6-Dimethylpyrazin-2(1H)-one features a stable pyrazinone core with two methyl groups at the 5 and 6 positions, enhancing electron density and enabling efficient integration into heterocyclic scaffolds. This bench-stable compound serves as a key building block in medicinal chemistry, particularly for developing kinase inhibitors and bioactive nitrogen-rich frameworks.

Application

5,6-Dimethylpyrazin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through established functionalization pathways. Its stability under standard reaction conditions and compatibility with diverse coupling strategies facilitate efficient access to substituted pyrazine derivatives. The molecule functions as a key intermediate in the development of kinase inhibitors and other pharmaceutical candidates, offering predictable reactivity and straightforward purification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   0.38674
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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