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CS-W001157 4
Total: USD 88.00

6-Methylsalicylic acid

  • CAS No. 567-61-3

  • Cat. No. CS-W002751
  • Purity≥98%
  • MDL No.MFCD01194284

*For research and further manufacturing use only, not for direct human use.

6-Methylsalicylic acid|CS-W002751

Structure of 567-61-3

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General Information

  • CAS No. 567-61-3
  • Cat. No. CS-W002751
  • Purity ≥98%
  • MDL No. MFCD01194284
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃
  • Molecular Weight 152.15
  • Synonym(s) None
  • SMILES OC1=CC=CC(C)=C1C(O)=O

Description

Neohesperidin dihydrochalcone hydrate, is a flavonoid sweetening agent with potent antioxidant activity. It is antioxidant agent. artificial sweetener.

Application

6-Methylsalicylic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its ortho-hydroxy carboxylic acid functionality supports facile derivatization via esterification, amidation, and cyclization reactions. The methyl group at the 6-position enhances metabolic stability and modulates electronic properties, improving utility in medicinal chemistry campaigns. Bench-stable and readily purified by recrystallization, it functions effectively in standard coupling and condensation protocols.

Synthesis

  • Route1

    References

    • Baur, Benjamin; Storch, Kirsten; Martz, Kathrin E.; Goettert, Marcia I.; Richters, Andre; Rauh, Daniel; Laufer, Stefan A. Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8561 - 8578
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    References

    • Silverman, F. Paul; Petracek, Peter D.; Heiman, Daniel F.; Fledderman, Christina M.; Warrior, Prem Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 25 p. 9775 - 9780
  • Route3
    • null|null
      56-23-5
    • null|null
      108-39-4
    • ~58%
    • In-stock
      6-Methylsalicylic acid|CS-W002751
      567-61-3
    • In-stock
      4-Hydroxy-2-methylbenzoic acid|CS-W016305
      578-39-2

    References

    • Journal of the American Chemical Society, , vol. 106, # 1 p. 174 - 178

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.39882
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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