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Structure of 56621-91-1
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2-Bromo-5-pyrimidinamine features a bromine atom at the 2-position and an amino group at the 5-position of the pyrimidine ring, creating a versatile scaffold for nucleophilic substitution and cross-coupling reactions. This electron-deficient heterocycle enables efficient derivatization in medicinal chemistry and materials science applications.
2-Bromo-5-pyrimidinamine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds through palladium-catalyzed cross-coupling reactions. Its bromine atom facilitates reliable C–X bond formation with aryl, heteroaryl, and alkyl boron reagents under standard Suzuki conditions. The amine group provides orthogonal reactivity for derivatization, while the compound exhibits excellent bench stability and ease of purification, making it well-suited for high-throughput synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H318-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: