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Structure of 566169-93-5
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Pittsburgh Compound B delivers high-affinity binding to cerebral amyloid-beta plaques, enabling non-invasive visualization of Alzheimer’s disease pathology via PET imaging. This radiolabeled tracer features a benzoylpyrrolidine scaffold with optimized pharmacokinetics for rapid brain penetration and clearance of background signal.
Pittsburgh Compound B serves as a well-established radioligand for in vivo imaging of beta-amyloid plaques in Alzheimer’s disease research. Its high binding affinity and selectivity for fibrillar amyloid-beta enable reliable positron emission tomography (PET) visualization, facilitating longitudinal studies of neurodegenerative progression. The compound exhibits favorable pharmacokinetics and metabolic stability in preclinical models, supporting consistent target engagement and signal-to-background ratios.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: