Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Pittsburgh Compound B

  • CAS No. 566169-93-5

  • Cat. No. CS-0092545
  • Purity≥95%
  • MDL No.MFCD17018727
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Pittsburgh Compound B|CS-0092545

Structure of 566169-93-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

Pittsburgh Compound B delivers high-affinity binding to cerebral amyloid-beta plaques, enabling non-invasive visualization of Alzheimer’s disease pathology via PET imaging. This radiolabeled tracer features a benzoylpyrrolidine scaffold with optimized pharmacokinetics for rapid brain penetration and clearance of background signal.

Application

Pittsburgh Compound B serves as a well-established radioligand for in vivo imaging of beta-amyloid plaques in Alzheimer’s disease research. Its high binding affinity and selectivity for fibrillar amyloid-beta enable reliable positron emission tomography (PET) visualization, facilitating longitudinal studies of neurodegenerative progression. The compound exhibits favorable pharmacokinetics and metabolic stability in preclinical models, supporting consistent target engagement and signal-to-background ratios.

General Information

  • CAS No. 566169-93-5
  • Cat. No. CS-0092545
  • Purity ≥95%
  • MDL No. MFCD17018727
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂OS
  • Molecular Weight 256.33
  • Synonym(s) PiB; 6-OH-BTA-1
  • SMILES OC1=CC=C2N=C(SC2=C1)C3=CC=C(C=C3)NC

Computational Chemistry Data

  • TPSA   45.15
  • LogP   3.7106
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Pittsburgh Compound B sigmaPittsburgh Compound B manufacturerPittsburgh Compound B pricePittsburgh Compound B structurePittsburgh Compound B SDSbuy Pittsburgh Compound BPittsburgh Compound B supplierPittsburgh Compound B usesPittsburgh Compound B molecular weightprice of Pittsburgh Compound BPittsburgh Compound B chemical name formula of Pittsburgh Compound B
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label