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CS-W001157 4
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1,2,3,4-Tetrahydronaphthalene-1-carbonitrile

  • CAS No. 56536-96-0

  • Cat. No. CS-W021269
  • Molecule weight157.22
  • Purity≥95%
  • MDL No.MFCD08703294

*For research and further manufacturing use only, not for direct human use.

1,2,3,4-Tetrahydronaphthalene-1-carbonitrile|CS-W021269

Structure of 56536-96-0

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General Information

  • CAS No. 56536-96-0
  • Cat. No. CS-W021269
  • Purity ≥95%
  • MDL No. MFCD08703294
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁N
  • Molecular Weight 157.22
  • Synonym(s) Tetralin-1-carbonitrile
  • SMILES N#CC1CCCC2=C1C=CC=C2

Description

1,2,3,4-Tetrahydronaphthalene-1-carbonitrile features a fused bicyclic core with a nitrile group at the 1-position, offering enhanced stability and solubility in organic media. This structure enables efficient integration into pharmaceutical intermediates and advanced synthetic scaffolds, particularly in asymmetric synthesis and heterocyclic ring formation.

Application

1,2,3,4-Tetrahydronaphthalene-1-carbonitrile serves as a versatile building block in medicinal chemistry and process development, enabling efficient access to substituted naphthyl scaffolds. The nitrile group provides a robust handle for transformation via hydrolysis, reduction, or nucleophilic addition, while the tetrahydroaromatic core offers enhanced metabolic stability and lipophilicity modulation. Its bench-stable nature and compatibility with standard reaction conditions facilitate straightforward incorporation into complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   2.63008
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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