Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 4-amino-3-hydroxybenzenecarboxylate

  • CAS No. 63435-16-5

  • Cat. No. CS-W000706
  • Purity≥95%
  • MDL No.MFCD00017093

*For research and further manufacturing use only, not for direct human use.

Methyl 4-amino-3-hydroxybenzenecarboxylate|CS-W000706

Structure of 63435-16-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 63435-16-5
  • Cat. No. CS-W000706
  • Purity ≥95%
  • MDL No. MFCD00017093
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight 167.16
  • Synonym(s) Methyl 4-amino-3-hydroxybenzoate
  • SMILES O=C(OC)C1=CC=C(N)C(O)=C1

Description

Methyl 4-amino-3-hydroxybenzenecarboxylate features a strategically positioned amino group and a phenolic hydroxyl, enabling dual functionalization in synthetic sequences. The methyl ester provides stability and facilitates downstream transformations. This ortho-substituted scaffold offers enhanced solubility and reactivity under standard conditions, supporting efficient incorporation into complex molecular architectures.

Application

Methyl 4-amino-3-hydroxybenzenecarboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. The molecule combines ortho-directed reactivity from the amino and hydroxyl groups with the electrophilic handle of the ester, facilitating regioselective functionalization. Its bench-stable nature and compatibility with standard coupling and cyclization protocols make it suitable for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      4-Amino-3-hydroxybenzoic acid|CS-W002114
      2374-03-0
    • ~94%
    • In-stock
      Methyl 4-amino-3-hydroxybenzenecarboxylate|CS-W000706
      63435-16-5

    References

    • ALMIRALL, S.A.; AIGUADE BOSCH, Jose; GUAL ROIG, Silvia; PRAT QUINONES, Maria; PUIG DURAN, Carlos Patent: WO2013/68554 A1, 2013 ; Location in patent: Page/Page column 80 ;
  • Route2

    References

    • US2003/220241 A1, ;
  • Route3
    • In-stock
      4-Amino-3-hydroxybenzoic acid|CS-W002114
      2374-03-0
    • null|null
      75-36-5
    • ~80%
    • In-stock
      Methyl 4-amino-3-hydroxybenzenecarboxylate|CS-W000706
      63435-16-5

    References

    • Jonckers, Tim H.M.; Rouan, Marie-Claude; Hache, Geerwin; Schepens, Wim; Hallenberger, Sabine; Baumeister, Judith; Sasaki, Jennifer C. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 15 p. 4998 - 5002

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   72.55
  • LogP   0.761
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 63435-16-5 sigma63435-16-5 manufacturer63435-16-5 price63435-16-5 structure63435-16-5 SDSbuy 63435-16-563435-16-5 supplier63435-16-5 uses63435-16-5 molecular weightprice of 63435-16-563435-16-5 chemical name formula of 63435-16-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label